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A computational model of liver tissue damage and repair
Drug induced liver injury (DILI) and cell death can result from oxidative stress in hepatocytes. An initial pattern of centrilobular damage in the APAP model of DILI is amplified by communication from stressed cells and immune system activation. While hepatocyte proliferation counters cell loss, hig...
Uloženo v:
| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7752149/ https://ncbi.nlm.nih.gov/pubmed/33347443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243451 |
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