Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity

PDGF/VEGF ligands regulate a plethora of biological processes in multicellular organisms via autocrine, paracrine, and endocrine mechanisms. We investigated organ-specific metabolic roles of Drosophila PDGF/VEGF-like factors (Pvfs). We combine genetic approaches and single-nuclei sequencing to demon...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ghosh, Arpan C, Tattikota, Sudhir Gopal, Liu, Yifang, Comjean, Aram, Hu, Yanhui, Barrera, Victor, Ho Sui, Shannan J, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752135/
https://ncbi.nlm.nih.gov/pubmed/33107824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56969
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