Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice

Changes in intracellular calcium levels in the sinus node modulate cardiac pacemaking (the calcium clock). Trimeric intracellular cation (TRIC) channels are counterion channels on the surface of the sarcoplasmic reticulum and compensate for calcium release from ryanodine receptors, which play a majo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Murakami, Manabu, Toyama, Yuichi, Yonekura, Manabu, Ohba, Takayoshi, Matsuzaki, Yasushi, Sawamura, Daisuke, Murakami, Agnieszka M., Nishi, Miyuki, Itagaki, Shirou, Tomita, Hirofumi, Takeshima, Hiroshi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751866/
https://ncbi.nlm.nih.gov/pubmed/33347504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244254
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