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Mechanisms of CDK4/6 Inhibitor Resistance in Luminal Breast Cancer

As a new-generation CDK inhibitor, a CDK4/6 inhibitor combined with endocrine therapy has been successful in the treatment of advanced estrogen receptor–positive (ER+) breast cancer. Although there has been overall progress in the treatment of cancer, drug resistance is an emerging cause for breast...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Li, Zhen, Zou, Wei, Zhang, Ji, Zhang, Yunjiao, Xu, Qi, Li, Siyuan, Chen, Ceshi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751736/
https://ncbi.nlm.nih.gov/pubmed/33364954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.580251
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