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A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells

IFNL2 is a potent antiviral interferon, but the regulation of its gene expression is not fully clear. Here, we report the regulation of ATG10S for IFNL2 transcription. Through sequential deletion of the IFNL2 promoter sequence, we found LP1-1, a fragment of the promoter responding to ATG10S activity...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Miao-Qing, Zhao, Qiong, Zhang, Jing-Pu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751675/
https://ncbi.nlm.nih.gov/pubmed/31996071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1719681
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