Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy

KPNA2/importin-alpha1 (karyopherin subunit alpha 2) is the primary nucleocytoplasmic transporter for some transcription factors to activate cellular proliferation and differentiation. Aberrant increase of KPNA2 level is identified as a prognostic marker in a variety of cancers. Yet, the turnover mec...

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Vydáno v:Autophagy
Hlavní autoři: He, Jia, Yang, Liping, Chang, Peixi, Yang, Shixing, Lin, Shaoli, Tang, Qiyi, Wang, Xinping, Zhang, Yan-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751636/
https://ncbi.nlm.nih.gov/pubmed/32924767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1823122
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