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Prevalence of HIV-1 Integrase Strand Transfer Inhibitor Resistance in Treatment-Naïve Voluntary Counselling and Testing Clients by Population Sequencing and Illumina Next-Generation Sequencing in Taiwan

PURPOSE: Integrase strand transfer inhibitors (INSTIs) are used as first-line therapy for HIV-1-infected patients. Next-generation sequencing (NGS) can detect low-frequency mutants; however, the clinical value of NGS to detect resistance variants is unknown. This study aimed to evaluate the prevalen...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Tsai, Hung-Chin, Chen, I-Tzu, Tsai, Kuo-Wang, Lee, Susan Shin-Jung, Chen, Yao-Shen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751586/
https://ncbi.nlm.nih.gov/pubmed/33364799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S273704
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