Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-β/Smad pathway

CONTEXT: Oral submucous fibrosis (OSF) is a chronic and progressive disease. Arecoline, present in betel nuts, has been proposed as a vital aetiological factor. However, the underlying mechanism remains unclear. OBJECTIVES: This research elucidates the expression of tropomyosin-1 (TPM1) and its regu...

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Dades bibliogràfiques
Publicat a:Pharm Biol
Autors principals: Li, Long, Gu, Liqun, Yao, Zhigang, Wang, Yuehong, Tang, Zhangui, Wu, Xiaoying
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751430/
https://ncbi.nlm.nih.gov/pubmed/33332205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1851729
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