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Melanoma-Derived Exosomes Endow Fibroblasts with an Invasive Potential via miR-21 Target Signaling Pathway

BACKGROUND: Tumor-derived exosomes are messengers that participate in tumor progression. Fibroblasts are associated with the metastasis of cancer depending on their cellular plasticity. We hypothesize that tumor-derived exosomes endow the fibroblasts in tumor microenvironment with invasive phenotype...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Wang, Chenmeiyi, Wang, Yiting, Chang, Xiulin, Ba, Xiaoyun, Hu, Na, Liu, Qing, Fang, Liaoqiong, Wang, Zhibiao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751322/
https://ncbi.nlm.nih.gov/pubmed/33364842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S273718
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