Initiation of immunotherapy with activated natural killer cells and anti-GD2 antibody dinutuximab prior to resection of primary neuroblastoma prolongs survival in mice

BACKGROUND: Immunotherapy with anti-disialoganglioside dinutuximab has improved survival for children with high-risk neuroblastoma (NB) when given after induction chemotherapy and surgery. However, disease recurrence and resistance persist. Dinutuximab efficacy has not been evaluated when initiated...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Main Authors: Zobel, Michael John, Zamora, Abigail K, Wu, Hong-wei, Sun, Jianping, Lascano, Danny, Malvar, Jemily, Wang, Larry, Sheard, Michael A, Seeger, Robert C, Kim, Eugene S
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751216/
https://ncbi.nlm.nih.gov/pubmed/33428582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001560
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