β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice

Sirtuins are a family of proteins that regulate biological processes such as cellular stress and aging by removing posttranslational modifications (PTMs). We recently identified several novel PTMs that can be removed by sirtuin 4 (SIRT4), which is found in mitochondria. We showed that mice with a gl...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Huynh, Frank K., Peterson, Brett S., Anderson, Kristin A., Lin, Zhihong, Coakley, Aeowynn J., Llaguno, Fiara M. S., Nguyen, Thi-Tina N., Campbell, Jonathan E., Stephens, Samuel B., Newgard, Christopher B., Hirschey, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750516/
https://ncbi.nlm.nih.gov/pubmed/32865009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00170.2020
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