The Suppression of miR-199a-3p by Promoter Methylation Contributes to Papillary Thyroid Carcinoma Aggressiveness by Targeting RAP2a and DNMT3a

BACKGROUND: It was previously demonstrated that miR-199a-3p plays an important role in tumor progression; especially, its down-regulation in papillary thyroid cancer (PTC) is associated with cancer cell invasion and proliferation. In the present report, we investigated the mechanism involved in the...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Cell Dev Biol
Main Authors: Wu, Feng, Lin, Xiao, Shan, Su-Kang, Li, Fuxingzi, Xu, Feng, Zhong, Jia-Yu, Guo, Bei, Zheng, Ming-Hui, Wang, Yi, Mo, Zhao-Hui, Yuan, Ling-Qing
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020
נושאים:
Cell and Developmental Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750465/
https://ncbi.nlm.nih.gov/pubmed/33365310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.594528
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