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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia

BACKGROUND: The mitochondrial cofactors α-lipoic acid (ALA), coenzyme Q10 (CoQ10) and carnitine (CARN) play distinct and complementary roles in mitochondrial functioning, along with strong antioxidant actions. Also termed mitochondrial nutrients (MNs), these cofactors have demonstrated specific prot...

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Publicat a:Inflamm Res
Autors principals: Pagano, Giovanni, Manfredi, Carla, Pallardó, Federico V., Lyakhovich, Alex, Tiano, Luca, Trifuoggi, Marco
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7750159/
https://ncbi.nlm.nih.gov/pubmed/33346851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-020-01423-0
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