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The voltage-gated proton channel Hv1 plays a detrimental role in contusion spinal cord injury via extracellular acidosis-mediated neuroinflammation

Tissue acidosis is an important secondary injury process in the pathophysiology of traumatic spinal cord injury (SCI). To date, no studies have examined the role of proton extrusion as mechanism of pathological acidosis in SCI. In the present study, we hypothesized that the phagocyte-specific proton...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Li, Yun, Ritzel, Rodney M, He, Junyun, Cao, Tuoxin, Sabirzhanov, Boris, Li, Hui, Liu, Simon, Wu, Long-Jun, Wu, Junfang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749852/
https://ncbi.nlm.nih.gov/pubmed/33039662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.10.005
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