Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

AIMS: Mesenchymal stromal/stem cell (MSC)-derived extracellular vesicles (EVs) shuttle select MSC contents and are endowed with an ability to repair ischemic tissues. We hypothesized that exposure to cardiovascular risk factors may alter the microRNA cargo of MSC-derived EVs, blunting their capacity...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Eirin, Alfonso, Ferguson, Christopher M., Zhu, Xiang-Yang, Saadiq, Ishran M., Tang, Hui, Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749840/
https://ncbi.nlm.nih.gov/pubmed/32592955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2020.101877
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