Cutaneous Wounds in Mice Lacking Tumor Necrosis Factor-stimulated Gene-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response

We investigated how loss of tumor necrosis factor-stimulated gene-6 (TSG-6) affects wound closure and skin inflammation. TSG-6 has several known biological functions including enzymatic transfer of heavy chain proteins (HC) from inter-α-trypsin inhibitor to hyaluronan (HA) to form HC-HA complexes. T...

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Bibliographic Details
Published in:J Invest Dermatol
Main Authors: Shakya, Sajina, Mack, Judith A., Alipour, Minou, Maytin, Edward V.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749718/
https://ncbi.nlm.nih.gov/pubmed/32422216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.04.015
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