SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity

Although ARID1A mutations are a hallmark feature, mutations in other SWI/SNF (SWItch/Sucrose Non-Fermentable) chromatin remodeling subunits are also observed in endometrial neoplasms. Here, we interrogated the roles of Brahma/SWI2-related gene 1 (BRG1, SMARCA4), the SWI/SNF catalytic subunit, in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Reske, Jake J, Wilson, Mike R, Holladay, Jeanne, Wegener, Marc, Adams, Marie, Chandler, Ronald L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
General Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749707/
https://ncbi.nlm.nih.gov/pubmed/33075803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa227
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