Identification of FDA approved drugs and nucleoside analogues as potential SARS-CoV-2 A1pp domain inhibitor: An in silico study

Coronaviruses are known to infect respiratory tract and intestine. These viruses possess highly conserved viral macro domain A1pp having adenosine diphosphate (ADP)-ribose binding and phosphatase activity sites. A1pp inhibits adenosine diphosphate (ADP)-ribosylation in the host and promotes viral in...

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Publicat a:Comput Biol Med
Autors principals: Singh, Atul Kumar, Kushwaha, Prem Prakash, Prajapati, Kumari Sunita, Shuaib, Mohd, Gupta, Sanjay, Kumar, Shashank
Format: Artigo
Idioma:Inglês
Publicat: Published by Elsevier Ltd. 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749648/
https://ncbi.nlm.nih.gov/pubmed/33352458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiomed.2020.104185
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