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Mammalian nuclear TRUB1, mitochondrial TRUB2, and cytoplasmic PUS10 produce conserved pseudouridine 55 in different sets of tRNA

Most mammalian cytoplasmic tRNAs contain ribothymidine (T) and pseudouridine (Ψ) at positions 54 and 55, respectively. However, some tRNAs contain Ψ at both positions. Several Ψ54-containing tRNAs function as primers in retroviral DNA synthesis. The Ψ54 of these tRNAs is produced by PUS10, which can...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Mukhopadhyay, Shaoni, Deogharia, Manisha, Gupta, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749629/
https://ncbi.nlm.nih.gov/pubmed/33023933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076810.120
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