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Mammalian nuclear TRUB1, mitochondrial TRUB2, and cytoplasmic PUS10 produce conserved pseudouridine 55 in different sets of tRNA

Most mammalian cytoplasmic tRNAs contain ribothymidine (T) and pseudouridine (Ψ) at positions 54 and 55, respectively. However, some tRNAs contain Ψ at both positions. Several Ψ54-containing tRNAs function as primers in retroviral DNA synthesis. The Ψ54 of these tRNAs is produced by PUS10, which can...

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Vydáno v:RNA
Hlavní autoři: Mukhopadhyay, Shaoni, Deogharia, Manisha, Gupta, Ramesh
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749629/
https://ncbi.nlm.nih.gov/pubmed/33023933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076810.120
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