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Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

BACKGROUND: Neurofibromatosis type 1 (NF1) is a multi‐organ disease caused by mutations in neurofibromin 1 (NF1). Amongst other features, NF1 patients frequently show reduced muscle mass and strength, impairing patients' mobility and increasing the risk of fall. The role of Nf1 in muscle and th...

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Detalhes bibliográficos
Publicado no:J Cachexia Sarcopenia Muscle
Main Authors: Wei, Xiaoyan, Franke, Julia, Ost, Mario, Wardelmann, Kristina, Börno, Stefan, Timmermann, Bernd, Meierhofer, David, Kleinridders, Andre, Klaus, Susanne, Stricker, Sigmar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749575/
https://ncbi.nlm.nih.gov/pubmed/33078583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12632
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