Next-Generation TLC: A Quantitative Platform for Parallel Spotting and Imaging

A high-throughput screening (HTS) approach for simultaneous analysis and quantification of the percent conversion of up to 48 reactions has been developed using a thin-layer chromatography (TLC) imaging method. As a test-bed reaction, we monitored 48 thiol conjugate additions to a Meldrum’s acid der...

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Detaylı Bibliyografya
Yayımlandı:J Org Chem
Asıl Yazarlar: Boulgakov, Alexander A., Moor, Sarah, Jo, Hyun Hwa, Metola, Pedro, Joyce, Leo A., Marcotte, Edward M., Welch, Christopher J., Anslyn, Eric V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748073/
https://ncbi.nlm.nih.gov/pubmed/32559382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c00349
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