Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx

Myocardial injury in sepsis may be caused by a burst of several inflammatory mediators, leading to vascular endothelial injuries. However, the contribution of neutrophil elastase (NE) to myocardial injury in sepsis is still unknown. We aimed to evaluate whether endotoxemia-induced myocardial injury...

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Dades bibliogràfiques
Publicat a:Shock
Autors principals: Fukuta, Tetsuya, Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Takada, Chihiro, Tomita, Hiroyuki, Suzuki, Akio, Oda, Kazumasa, Uchida, Akihiro, Matsuo, Saori, Fukuda, Hirotsugu, Yano, Hirohisa, Muraki, Isamu, Zaikokuji, Ryogen, Kuroda, Ayumi, Nishio, Ayane, Sampei, So, Miyazaki, Nagisa, Hotta, Yasuaki, Yamada, Noriaki, Watanabe, Takatomo, Morishita, Kentaro, Doi, Tomoaki, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Maekawa, Yoichi, Ogura, Shinji
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
Matèries:
Basic Science Aspects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748054/
https://ncbi.nlm.nih.gov/pubmed/31764619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000001482
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