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Navigating the path to distant metastasis
How ‘difficult’ is it for somatic evolution to produce a cell that is capable of leaving the primary tumor and growing in a distant organ? In this issue, Reiter et al. assess genetic diversity across metastatic lesions and identify a tight selective bottleneck preceding distant metastasis.
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| Publicado no: | Nat Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7747770/ https://ncbi.nlm.nih.gov/pubmed/32632324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0660-z |
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