DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway

Collagen type VI (COL6) deposition occurs in various glomerular diseases, causing serious pathological damage like nodular lesions. However, the mechanisms underlying the deposition of COL6 remain unclear. In renal biopsy samples, immunohistochemical analyses revealed that COL6 and phosphorylated hi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Fujii, Ai, Sunatani, Yumi, Furuichi, Kengo, Fujimoto, Keiji, Adachi, Hiroki, Iwabuchi, Kuniyoshi, Yokoyama, Hitoshi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747722/
https://ncbi.nlm.nih.gov/pubmed/33335142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79106-3
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