DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway

Collagen type VI (COL6) deposition occurs in various glomerular diseases, causing serious pathological damage like nodular lesions. However, the mechanisms underlying the deposition of COL6 remain unclear. In renal biopsy samples, immunohistochemical analyses revealed that COL6 and phosphorylated hi...

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Publicat a:Sci Rep
Autors principals: Fujii, Ai, Sunatani, Yumi, Furuichi, Kengo, Fujimoto, Keiji, Adachi, Hiroki, Iwabuchi, Kuniyoshi, Yokoyama, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747722/
https://ncbi.nlm.nih.gov/pubmed/33335142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79106-3
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