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Nonhuman primate to human immunobridging to infer the protective effect of an Ebola virus vaccine candidate

It has been proven challenging to conduct traditional efficacy trials for Ebola virus (EBOV) vaccines. In the absence of efficacy data, immunobridging is an approach to infer the likelihood of a vaccine protective effect, by translating vaccine immunogenicity in humans to a protective effect, using...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Roozendaal, Ramon, Hendriks, Jenny, van Effelterre, Thierry, Spiessens, Bart, Dekking, Liesbeth, Solforosi, Laura, Czapska-Casey, Dominika, Bockstal, Viki, Stoop, Jeroen, Splinter, Daniel, Janssen, Sarah, Baelen, Ben van, Verbruggen, Nadia, Serroyen, Jan, Dekeyster, Eline, Volkmann, Ariane, Wollmann, Yvonne, Carrion, Ricardo, Giavedoni, Luis D., Robinson, Cynthia, Leyssen, Maarten, Douoguih, Macaya, Luhn, Kerstin, Pau, Maria Grazia, Sadoff, Jerry, Vandebosch, An, Schuitemaker, Hanneke, Zahn, Roland, Callendret, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747701/
https://ncbi.nlm.nih.gov/pubmed/33335092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00261-9
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