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Impact of Hereditary Pancreatitis on Patients and their Families

Hereditary pancreatitis (HP), a highly penetrant (~80%) autosomal dominant disease associated with PRSS1 variants, causes acute pancreatitis (AP) in childhood and chronic pancreatitis (CP) by early adulthood. Other clinical features include pain, diabetes and risk of pancreatic cancer. HP kindreds w...

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Detalhes bibliográficos
Publicado no:J Genet Couns
Main Authors: Shelton, Celeste A., Grubs, Robin E., Umapathy, Chandraprakash, Yadav, Dhiraj, Whitcomb, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747647/
https://ncbi.nlm.nih.gov/pubmed/32026589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgc4.1221
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