Population pharmacokinetic analysis of doripenem for Japanese patients in intensive care unit

We aimed to construct a novel population pharmacokinetics (PPK) model of doripenem (DRPM) for Japanese patients in intensive care unit, incorporating the clearance of DRPM by continuous renal replacement therapy (CRRT). Twenty-one patients treated with DRPM (0.25 or 0.5 g) by intravenous infusion ov...

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Publicat a:Sci Rep
Autors principals: Nonoshita, Ko, Suzuki, Yosuke, Tanaka, Ryota, Kaneko, Tetsuya, Ohchi, Yoshifumi, Sato, Yuhki, Yasuda, Norihisa, Goto, Koji, Kitano, Takaaki, Itoh, Hiroki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747597/
https://ncbi.nlm.nih.gov/pubmed/33335198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79076-6
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