7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor

7,3′,4′-Trihydroxyisoflavone (7,3′,4′-THIF) is a metabolite of daidzein which is a representative isoflavone found in soybean. Recent studies suggested that 7,3′,4′-THIF exerts a hypopigmentary effect in B16F10 cells, however, its underlying molecular mechanisms and specific target protein remain un...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Kim, Ji Hye, Lee, Jae-Eun, Kim, Taewon, Yeom, Myung Hun, Park, Jun Seong, di Luccio, Eric, Chen, Hanyong, Dong, Zigang, Lee, Ki Won, Kang, Nam Joo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747307/
https://ncbi.nlm.nih.gov/pubmed/33344501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.577284
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