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Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B

[Image: see text] Monoamine oxidase B (MAO-B) is an important enzyme regulating the levels of monoaminergic neurotransmitters. Selective MAO-B inhibitors have been labeled with carbon-11 or fluorine-18 to visualize the localization of MAO-B in vivo by positron emission tomography (PET) and thereby h...

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Publicat a:ACS Chem Neurosci
Autors principals: Nag, Sangram, Jia, Zhisheng, Svedberg, Marie, Jackson, Alex, Ahmad, Rabia, Luthra, Sajinder, Varnäs, Katarina, Farde, Lars, Halldin, Christer
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747220/
https://ncbi.nlm.nih.gov/pubmed/33284012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00631
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