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Targeted tPA overexpression in denervated spinal motor neurons promotes stroke recovery in mice

Our previous studies demonstrated that axonal remodeling of the corticospinal tract (CST) contributes to neurological recovery after stroke in rodents. The present study employed a novel non-invasive peripheral approach, to over-express tPA in denervated spinal motor neurons via recombinant adeno-as...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Gan, Xinling, Chopp, Michael, Xin, Hongqi, Wang, Fengjie, Golembieski, William, Lu, Mei, He, Li, Liu, Zhongwu
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747163/
https://ncbi.nlm.nih.gov/pubmed/31987011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20901686
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