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Targeted tPA overexpression in denervated spinal motor neurons promotes stroke recovery in mice

Our previous studies demonstrated that axonal remodeling of the corticospinal tract (CST) contributes to neurological recovery after stroke in rodents. The present study employed a novel non-invasive peripheral approach, to over-express tPA in denervated spinal motor neurons via recombinant adeno-as...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cereb Blood Flow Metab
Päätekijät: Gan, Xinling, Chopp, Michael, Xin, Hongqi, Wang, Fengjie, Golembieski, William, Lu, Mei, He, Li, Liu, Zhongwu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747163/
https://ncbi.nlm.nih.gov/pubmed/31987011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X20901686
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