Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility

OBJECTIVE: Schizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are crucial to regulating the synaptic transmission and func...

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Vydáno v:Front Genet
Hlavní autoři: Hu, Tsung-Ming, Wang, Ying-Chieh, Wu, Chia-Liang, Hsu, Shih-Hsin, Tsai, Hsin-Yao, Cheng, Min-Chih
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746813/
https://ncbi.nlm.nih.gov/pubmed/33343614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.524258
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