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Impact of downstream effects of glucocorticoid receptor dysfunction on organ function in critical illness-associated systemic inflammation

Glucocorticoids (GCs) are stress hormones that regulate developmental and physiological processes and are among the most potent anti-inflammatory drugs to suppress chronic and acute inflammation. GCs act through the glucocorticoid receptor (GR), a ubiquitously expressed ligand-activated transcriptio...

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Detalles Bibliográficos
Publicado en:Intensive Care Med Exp
Main Authors: Wepler, Martin, Preuss, Jonathan M., Merz, Tamara, McCook, Oscar, Radermacher, Peter, Tuckermann, Jan P., Vettorazzi, Sabine
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746781/
https://ncbi.nlm.nih.gov/pubmed/33336296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-020-00325-z
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