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Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models

Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug. Many reports have described the efficacy of intranasal OXT therapy to improve the core symptoms of patients with A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Horiai, Machi, Otsuka, Ayano, Hidema, Shizu, Hiraoka, Yuichi, Hayashi, Ryotaro, Miyazaki, Shinji, Furuse, Tamio, Mizukami, Hiroaki, Teruyama, Ryoichi, Tamura, Masaru, Bito, Haruhiko, Maejima, Yuko, Shimomura, Kenju, Nishimori, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746761/
https://ncbi.nlm.nih.gov/pubmed/33335150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79109-0
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