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Nrf2: The Master and Captain of Beta Cell Fate
Prolonged hyperglycemia is toxic to pancreatic β-cells, generating excessive reactive oxygen species, defective glucose-stimulated insulin secretion, decreased insulin production, and eventually β-cell death and diabetes. Nrf2 is a master regulator of cellular responses to counteract dangerous level...
Tallennettuna:
| Julkaisussa: | Trends Endocrinol Metab |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7746592/ https://ncbi.nlm.nih.gov/pubmed/33243626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2020.11.002 |
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