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Role of VPS13, a protein with similarity to ATG2, in physiology and disease

The evolutionarily conserved VPS13 family proteins have been implicated in several cellular processes. Mutations in each of the four human VPS13s cause neurodevelopmental or neurodegenerative disorders. Until recently, the molecular function of VPS13 remained elusive. Genetic, functional and structu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Genet Dev
Hauptverfasser: Ugur, Berrak, Hancock-Cerutti, William, Leonzino, Marianna, De Camilli, Pietro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746581/
https://ncbi.nlm.nih.gov/pubmed/32563856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.05.027
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