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The therapeutic value of XL388 in human glioma cells

XL388 is a highly efficient and orally-available ATP-competitive PI3K-mTOR dual inhibitor. Its activity against glioma cells was studied here. In established and primary human glioma cells, XL388 potently inhibited cell survival and proliferation as well as cell migration, invasion and cell cycle pr...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhong, Shan, Xue, Jun, Cao, Jiao-Jiao, Sun, Bomin, Sun, Qing-Fang, Bian, Liu-Guan, Hu, Liang-Yun, Pan, Si-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746352/
https://ncbi.nlm.nih.gov/pubmed/33159013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103791
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