Optimised generation of iPSC-derived macrophages and dendritic cells that are functionally and transcriptionally similar to their primary counterparts

Induced pluripotent stem cells (iPSC) offer the possibility to generate diverse disease-relevant cell types, from any genetic background with the use of cellular reprogramming and directed differentiation. This provides a powerful platform for disease modeling, drug screening and cell therapeutics....

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Опубликовано в: :PLoS One
Главные авторы: Monkley, Susan, Krishnaswamy, Jayendra Kumar, Göransson, Melker, Clausen, Maryam, Meuller, Johan, Thörn, Kristofer, Hicks, Ryan, Delaney, Stephen, Stjernborg, Louise
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746299/
https://ncbi.nlm.nih.gov/pubmed/33332401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243807
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