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3D genome evolution and reorganization in the Drosophila melanogaster species group

Topologically associating domains, or TADs, are functional units that organize chromosomes into 3D structures of interacting chromatin. TADs play an important role in regulating gene expression by constraining enhancer-promoter contacts and there is evidence that deletion of TAD boundaries leads to...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Torosin, Nicole S., Anand, Aparna, Golla, Tirupathi Rao, Cao, Weihuan, Ellison, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746282/
https://ncbi.nlm.nih.gov/pubmed/33284803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009229
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