Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly

Bunyavirus ribonucleoprotein (RNP) that is assembled by polymerized nucleoproteins (N) coating a viral RNA and associating with a viral polymerase can be both the RNA synthesis machinery and the structural core of virions. Bunyaviral N and RNP thus could be assailable targets for host antiviral defe...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Mo, Qiong, Xu, Zhao, Deng, Fei, Wang, Hualin, Ning, Yun-Jia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746268/
https://ncbi.nlm.nih.gov/pubmed/33284835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009129
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