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Complement controls the immune synapse and tumors control complement
The synapses between immune cells and their targets are 150 Å wide. They regulate immune cell responses (IRs) to cognate antigens. Here, I outline a potential mechanism for self-nonself discrimination based on the C3d and iC3b proteolytic fragments of complement protein C3. The proposed C3 checkpoin...
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| Publicado no: | J Immunother Cancer |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745530/ https://ncbi.nlm.nih.gov/pubmed/33323465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001712 |
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