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Mechanism of Diuresis and Natriuresis by Cannabinoids: Evidence for Inhibition of Na(+)-K(+)-ATPase in Mouse Kidney Thick Ascending Limb Tubules
The endocannabinoid, anandamide (AEA), stimulates cannabinoid receptors (CBRs) and is enriched in the kidney, especially the renal medulla. AEA infused into the renal outer medulla of mice stimulates urine flow rate and salt excretion. Here we show that these effects are blocked by the CBR type 1 (C...
Zapisane w:
| Wydane w: | J Pharmacol Exp Ther |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745087/ https://ncbi.nlm.nih.gov/pubmed/33087396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000163 |
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