An update to the Monro–Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke

High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to prevent raised ICP. Serendipitous observations in intracereb...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Kalisvaart, Anna C. J., Wilkinson, Cassandra M., Gu, Sherry, Kung, Tiffany F. C., Yager, Jerome, Winship, Ian R., van Landeghem, Frank K. H., Colbourne, Frederick
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7745016/
https://ncbi.nlm.nih.gov/pubmed/33328490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78880-4
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