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Influence of fluorophore and linker length on the localization and trafficking of fluorescent sterol probes

Fluorescent sterol probes, comprising a fluorophore connected to a sterol backbone by means of a linker, are promising tools for enabling high-resolution imaging of intracellular cholesterol. In this study, we evaluated how the size of the linker, site of its attachment and nature of the fluorophore...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Králová, Jarmila, Jurášek, Michal, Mikšátková, Lucie, Marešová, Anna, Fähnrich, Jan, Cihlářová, Petra, Drašar, Pavel, Bartůněk, Petr, Král, Vladimír
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7745015/
https://ncbi.nlm.nih.gov/pubmed/33328481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78085-9
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