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Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel
SthK, a cyclic nucleotide-modulated ion channel from Spirochaeta thermophila, activates slowly upon cAMP increase. This is reminiscent of the slow, cAMP-induced activation reported for the hyperpolarization-activated and cyclic nucleotide-gated channel HCN2 in the family of so-called pacemaker chann...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7744796/ https://ncbi.nlm.nih.gov/pubmed/33328472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20104-4 |
| Oznake: |
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