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Epilepsy protein Efhc1/myoclonin1 is expressed in cells with motile cilia but not in neurons or mitotic apparatuses in brain

EFHC1 gene encodes the myoclonin1 protein, also known as Rib72-1. Pathogenic variants in EFHC1 have been reported in patients with juvenile myoclonic epilepsy (JME). Although several studies of immunohistological investigations reproducibly showed that the myoclonin1 is expressed in cells with flage...

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Pubblicato in:Sci Rep
Autori principali: Suzuki, Toshimitsu, Inoue, Ikuyo, Yamakawa, Kazuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744795/
https://ncbi.nlm.nih.gov/pubmed/33328576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79202-4
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