Modulating glutathione thiol status alters pancreatic β-cell morphogenesis in the developing zebrafish (Danio rerio) embryo

Emerging evidence suggests that redox-active chemicals perturb pancreatic islet development. To better understand potential mechanisms for this, we used zebrafish (Danio rerio) embryos to investigate roles of glutathione (GSH; predominant cellular redox buffer) and the transcription factor Nrf2a (Nf...

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Detalles Bibliográficos
Publicado en:Redox Biol
Autores principales: Rastogi, Archit, Severance, Emily G., Jacobs, Haydee M., Conlin, Sarah M., Islam, Sadia T., Timme-Laragy, Alicia R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744774/
https://ncbi.nlm.nih.gov/pubmed/33321464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101788
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