BSA-Stabilized Mesoporous Organosilica Nanoparticles Reversed Chemotherapy Resistance of Anaplastic Thyroid Cancer by Increasing Drug Uptake and Reducing Cellular Efflux

Anaplastic thyroid cancer (ATC) is a highly aggressive and the most lethal type of thyroid cancer. The standard-of-care for unresectable ATC is radiotherapy and chemotherapy, usually based on doxorubicin (Dox). However, most patients develop resistance shortly after treatment. To overcome the drug r...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Han, Xiao, Xu, Xiaoquan, Tang, Yuxia, Zhu, Feipeng, Tian, Ying, Liu, Wei, He, Doudou, Lu, Guangming, Gu, Yunfei, Wang, Shouju
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744685/
https://ncbi.nlm.nih.gov/pubmed/33344508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.610084
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