Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor

Severe hypercholesterolemia (HC) is defined as an elevation of total cholesterol (TC) due to the increase in LDL cholesterol (LDL-C) >95th percentile or 190 mg/dl. The high values of LDL-C, especially when it is maintained over time, is considered a risk factor for the development of atherosclero...

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Bibliographic Details
Published in:Front Genet
Main Authors: Jarauta, Estíbaliz, Bea-Sanz, Ana Ma, Marco-Benedi, Victoria, Lamiquiz-Moneo, Itziar
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744656/
https://ncbi.nlm.nih.gov/pubmed/33343620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.554931
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