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Subtle Influence of ACE2 Glycan Processing on SARS-CoV-2 Recognition

The severity of SARS-CoV-2 infection is highly variable and yet the molecular basis for this effect remains elusive. One potential contribution are differences in the glycosylation of target human cells, particularly as SARS-CoV-2 has the capacity to bind sialic acid which is a common, and highly va...

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Pubblicato in:J Mol Biol
Autori principali: Allen, Joel D., Watanabe, Yasunori, Chawla, Himanshi, Newby, Maddy L., Crispin, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744274/
https://ncbi.nlm.nih.gov/pubmed/33340519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166762
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