The nuclear DICER–circular RNA complex drives the deregulation of the glioblastoma cell microRNAome

The assortment of cellular microRNAs (“microRNAome”) is a vital readout of cellular homeostasis, but the mechanisms that regulate the microRNAome are poorly understood. The microRNAome of glioblastoma is substantially down-regulated in comparison to the normal brain. Here, we find malfunction of the...

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Udgivet i:Sci Adv
Main Authors: Bronisz, A., Rooj, A. K., Krawczyński, K., Peruzzi, P., Salińska, E., Nakano, I., Purow, B., Chiocca, E. A., Godlewski, J.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744081/
https://ncbi.nlm.nih.gov/pubmed/33328224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc0221
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